Know Thrombosis

Know thrombosis

Thrombosis is the formation of a blood clot in a blood vessel.

Thrombosis is the formation of a blood clot in a blood vessel. Blood clot formation can occur in any vein or artery throughout the body—for example, deep vein thrombosis (DVT) affects leg veins, while arterial thrombosis impacts coronary arteries. The blood clot itself is medically termed a thrombus. Once a blood clot forms, it can slow or completely block normal blood flow and may even break loose and travel to vital organs like the lungs, brain or heart. When a blood clot travels through the circulation, it becomes a dangerous embolism.

Thrombosis serves as the often preventable underlying cause of three major cardiovascular killers: heart attack, thromboembolic stroke and venous thromboembolism (VTE). These blood clot-related conditions represent the top three cardiovascular causes of death worldwide, making thrombosis awareness and blood clot prevention critically important for public health.

Types of Thrombosis

1

in

4

People WorldWide

are dying from conditions

caused by thrombosis.

And, it’s a startling fact that up to 900,000 people in the United States alone are affected by blood clots each year; about 100,000 of those people will die, which is greater than the total number of people who lose their lives each year to AIDS, breast cancer, and motor vehicle crashes combined.

Knowing the signs and symptoms of thrombosis could save your life.

Recognizing blood clot warning signs—such as leg pain, leg swelling, warmth in the limb, chest pain, shortness of breath or coughing up blood—can mean the difference between timely medical intervention and a life-threatening blood clot emergency.

Blood clot symptom awareness empowers individuals to seek prompt medical attention when experiencing these DVT and PE symptoms, potentially preventing severe thrombosis complications and saving lives. Knowing the most common blood clot signs and symptoms is crucial for early detection and treatment success.

For detailed information about specific DVT symptoms, PE warning signs and when to seek immediate medical care, visit our comprehensive guide to blood clot signs and symptoms to learn how to identify potentially life-threatening blood clot symptoms.

Learn More about blood clot signs and symptoms
Do you know thrombosis? Learn more with WTD

It’s a life-threatening condition that requires immediate medical attention.

If you notice these blood clot warning signs, seek emergency medical care immediately to prevent severe life-threatening outcomes. Prompt blood clot treatment can be life-saving when started quickly. Modern thrombosis treatment options include anticoagulant medications, thrombolytic therapy and advanced device-based treatments designed to prevent clot growth, dissolve existing clots and restore healthy blood flow.

To learn more about effective blood clot treatment options and how healthcare professionals tailor therapy to individual patient needs, visit our comprehensive thrombosis treatment page.

Learn More About Treatment

Recovery

Post-thrombotic syndrome (PTS) is a common blood clot complication that affects many DVT survivors and can become a disabling long-term condition requiring ongoing management. Blood clot recovery often involves managing both physical PTS symptoms and psychological challenges that impact quality of life for thrombosis survivors. For comprehensive information about post-thrombotic syndrome treatment, mental health support and living well during blood clot recovery, visit our blood clot recovery page.

Learn more about blood clot recovery

Are you at risk for developing a blood clot?

Blood clots affect people of all ages, races and ethnicities, occurring equally in both men and women, making it important to know thrombosis. However, specific blood clot risk factors and high-risk situations can significantly increase your chances of developing dangerous blood clots like deep vein thrombosis (DVT) or pulmonary embolism (PE).

VTE Risk Assessment: Essential Blood Clot Screening Tool

To identify patients at risk for blood clots, healthcare professionals should conduct a comprehensive VTE risk assessment—a specialized screening tool or questionnaire that evaluates critical risk factors including patient age, medical history, current medications and specific lifestyle factors. This blood clot risk evaluation helps medical providers determine a patient’s potential risk level (high, moderate or low risk) for developing life-threatening blood clots in the legs (DVT) or lungs (pulmonary embolism).

Hospital Blood Clot Prevention: Know Your Rights

If you are admitted to a hospital and don’t receive a VTE risk assessment for blood clot prevention, be proactive about your healthcare and specifically request this important blood clot screening. Hospital-acquired blood clots are preventable with proper risk assessment and prevention protocols.

The most common blood clot risk factors include recent surgery or hospitalization, prolonged immobility (like long flights or bed rest), advanced age (over 60), pregnancy and postpartum periods, hormone therapy or birth control pills, active cancer treatment, family history of blood clots, obesity, and smoking. Additional DVT and PE risk factors include previous blood clot history, heart disease, inflammatory conditions and certain genetic clotting disorders.

Read about blood clot risk factors here.

The most common blood clot symptoms vary depending on location but include leg pain, swelling, warmth and redness for deep vein thrombosis (DVT), and sudden shortness of breath, chest pain, rapid heart rate, and coughing up blood for pulmonary embolism (PE). Blood clot warning signs often develop gradually but can become life-threatening without prompt medical attention.

Learn more about the signs and symptoms of blood clots here.

Every hospitalized patient should request a VTE risk assessment—a blood clot screening tool that evaluates your risk for dangerous blood clots during surgery, extended bed rest or medical procedures. You can learn more about VTE risk assessments by clicking here.

  • A blood test called a D-dimer.
  • An ultrasound of the arm or leg to look for the DVT.
  • A CAT scan of the chest with intravenous dye to look for a PE.

Learn more about blood clot treatment options here.

Yes, blood clot prevention is highly effective using proven prophylaxis strategies. Blood clot prevention methods include anticoagulant medications (blood thinners), mechanical compression devices like compression stockings and pneumatic compression pumps, and early mobilization through movement and leg exercises.

  • Anticoagulant medications are the most common blood clot prevention treatment for high-risk patients during surgery or hospitalization.
  • Mechanical compression devices improve blood circulation and prevent DVT formation by maintaining healthy blood flow in the legs.
  • Early mobilization involves moving around and performing foot exercises as soon as medically possible to prevent thrombosis during bed rest.

Learn more about blood clot treatment options here.

10 million

Every year, there are approximately 10 million cases of VTE worldwide.*

About 100,000 of those people will die, which is greater than the total number of people who lose their lives each year to AIDS, breast cancer, and motor vehicle crashes combined.

Emerging data have enhanced the understanding of cancer-associated thrombosis, a major cause of morbidity and mortality and indicates that cancer patients are at four times higher risk than the general population of developing serious blood clots.

60%

Up to 60 percent of VTE cases occur during or after hospitalization, making it a leading cause of preventable death.*

4x Higher

Patients with cancer are four times more likely than the general population to develop serious blood clots.

Others include cancer-associated thrombosis and gender-specific risks.

Donate to the World Thrombosis Day campaign

Your contribution helps fund vital research, education and advocacy efforts that save lives from blood clots. Make a donation today to support our mission of reducing preventable deaths from thrombosis worldwide.

Donate Now

Share your story

Your experience with thrombosis can inspire others and raise awareness about this serious condition. Submit your story to help us educate the public and show that survivors and families are not alone in this fight.

Share your story

Take Action

Take bold action with World Thrombosis Day! Discover a wealth of engaging opportunities to make a profound difference. Your involvement can be a life-saving force. Explore the options and become a catalyst for change today.

Get Started